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  • I get that the big bad is nuts in the head, but really, if his plan is actually instrumentality as opposed to "I need a clever conversation piece and a novelty coffee table just ain't gonna cut it," you'd think Sign No. 1 that turning mankind into an ATM machine wasn't gonna pan out was that its biology only worked when supplemented with life-support machines. I know, Excuse Plot and all, but damn, Mad Scientist Guy, you could've done much more awesomely horrible things than slake your desire for corporophagiaphilia.
  • As noted on the main page, how in God's name are they going to justify making another centipede in the sequel? The doctor has a protege? The military decides there's some merit to researching this?
    • Well, we don't physically see Middle Piece (forgot her actual name) die on screen, which in horror movie language means she'll survive in the sequel, so my guess is that either she or whoever rescues her will carry on Heiter's idea.
      • Hmyea... given what was done to her, though, I might say that, if she managed to survive, she's one wreck of a person and not likely to carry on with that.
  • What was up with the second cop not saying or really doing anything? I couldn't help but think that was really weird to have that character here and not have him actually do anything. Even assuming it's an investor who was promised an appearance or something, you'd think they'd have him say at least one line.
    • He was The Voiceless. Both cops are played by real actors. The director wanted the second detective to be quiet and have piercing eyes and be unnerving.
  • How was the girl that ended up in the middle not able to carry her friend in the attempted escape? The friend weighed atmost 140 pounds. She should have been able to carry her friend, not have to struggle just to barely be able to drag her. T He effort put into the dragging also brings up another thing. How were her feet not cut when she was walking on the glass, or her freinds legs not cut when being drug through the glass?
    • For the first point, I'm pretty sure unconcious people are quite heavy and she wasn't very experienced with carrying people or how to carry them. Second point, no idea.
      • Second point answer: actually, they were. If you remember (and if you don't, seriously, does it really bear a repeat watching?) her incessant, annoying and anything but stealthy whining got worse as she crossed the glass. Also, there is a barely noticeable trail of blood left in their wake as she drags the other girl. It's hard to see because of the angle of the shot and because it's raining, but it is there.
      • As someone that has tried to help up a partially conscious person(not drunk), it really is that difficult when the other person is unable to assist. Had she been thinking, she should have put her into a fireman's carry from the bed; though it is possible to do it from the ground as well.
  • Why was the woman at the end where ass bandages when she had no surgery performed there?
    • If she didn't have the bandages, we'd see her bare ass for the whole movie, possibly more, and that would get to be distracting. EXTREMELY distracting.
    • It was probably a diaper for urination. Dr. Heiter didn't have enough time to toilet train his human centipede.
  • Why the hell did those two girls trust doctor Heiter and drank a glass of water from him? I know that they were pretty stupid but come on, it was just baffling that they trusted him.
  • Why is it that the people that only get a small dose of the drug start vomiting? The detective and the girl coughing and vomiting after a while, but the other girl simply passed out after having a full dose.
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