Worth pointing out, the jokes at Jason's expense were all kidding, based off something Angry Joe said, which resulted in everyone coming up with increasingly harsher variants of "I hate you, but here's a cool video."
Nik: That's gotta be some sort of new BDSM practice.
Joe: No, it's big, it's a big head...
Skitch: I'm sure it is.
Joe:The one on the top of your body!!
Nik: Oh wow, that's a big'un.
Everything involving the burning mattress.
The final confrontation with Talbot, wherein he holds the Queen at knifepoint, insults Vane's father to mentally attack him, and is generally a Smug Snake throughout, only to be thrown off his edge by two well-chosen words.
Talbot: "...and if you don't give me what I want... well, who is to say you didn't assassinate her on our wedding night?"
Viktor: *completely deadpan* "The King."
Talbot: "...oh." *cue epic defeat*
Spoony playing with his headset's voice changer in the 11/28 update, using the robotic voice mask to play RoboCop, a Dalek, Zordon, and the Killer Robot from RoboWar. He makes good use of it later on in the session when the group encounters a demon.
Don't you dare forget "Pika Pika".
Along with The Lollipop Guild, Zero Wing and DARK ENERGON. The voice filter shenanigans hijacked the actual proceedings of the session for a good ten minutes (not to mention the subsequent technical difficulties), but was completely worth it.
Do cancelled sessions count? When Spoony was forced to cancel the 11/14 session (after realizing he consulted the wrong edition of his guidebook during planning), several campaign members attempted to play a Doctor Who RPG--with Angry Joe, the person with the least knowledge of the show, playing as the Doctor. It started with Joe attempting to steal weapons from a Roman centurion, and went downhill from there...
Spoony: Okay, you awaken in your TARDIS--
Joe:(deadpan) What's a "Retardis"?
Linkara, the resident Whovian of the group, was laughing so hard that he had to excuse himself while he regained his composure.
Drunk Rollo T, depressed about the NY Giants losing their 21 point lead and the game, arriving late on the 12/19 session bringing hilarity.
Y Ruler of Time: Viktor proceeds to use Juliet's face as an axe. "You need sharpen your teeth to be better axe!" *impact sounds*
LordKaT: Why does my face hurt...?
That session happened to be Linkara's first; as such, he was trying to make a good impression on the group. So, when the party came upon an ancient stone coffin guarded by a vile demon, Bayban...well, it's best to let Rollo T describe what happened next:
"Now was Bayban’s time to impress. He introduced himself as an enigma; a man whose legends cast fear into the hearts who know of his deeds. Was he a hero? Was he a villain? All we knew was that wherever he went death seemed to follow. What would happen when Bayban the Butcher swung his bloodstained axe?! ....He botched and split his pants. No, seriously. He botched, and the botched roll said that he damages a piece of clothing. What an awkward roll. I think we said he tore his cloak, but it’s so much funnier to imagine this big armored hulk of a Paladin trying to swing his weapon and instead ripping his pants. Sorry Linkara, but that will forever be Bayban’s legacy to me. Welcome to D&D."
In the first video of the Epic Sessions, Vane II gets jumpy when he thinks people are speaking ill of his father. RolloT decides to milk this for all it's worth, firing off Stealth Insults by saying honest compliments then laughing afterwards ("Your father was a great man. *snerk*"), which drives Vane II nuts. Garret sums it up nicely at the end:
Garret: Wow Juliet, you're such a bitch!
The party has captured a pair of mercenaries who were sent to kill them. Grae offers one of them the following deal: Give us all of your gold, and we'll let you live. The mercenary says nothing and just stares at Grae defiantly, who proceeds to execute him on the spot and offer the same deal to the other mercenary, who informs Grae that all their gold is in the packs that he already took from them. Grae: "Oh, well, I guess you can go then."
2/20/11 - Bayban's just followed his nose to get some food, and some drunks are none too pleased at seeing the Paladin walk in, so one of them spits on him and attempts to call him out. Before the guy can, Bayban grabs him by the throat, hits his head on the bar, tells off the drunks, and sends them all packing. The funny part? He then proceeds to calmly go over to the half orc running the establishment, order a round of drinks and dinner for his compatriots like nothing ever happened. Someone in the chat put it best - "Bayban the bipolar." (The change in Lewis's voice as he plays the character is what really makes it hilarious.)
Intimidating Bayban: Excuse me, sir, but if you think the monsters are "coming" then you are obviously too drunk to see anything clearly, because the monster's right in front of you!. SO I SUGGEST. YOU. RUN!
At the start of one session, Y Ruler of Time was running late, Lord Kat asked a British friend to fill in and play Viktor in the meantime. When Y finally shows up, the guys have a good bit of fun over the whole thing.