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Based off a three part series of light novels by Yuya Aoki, creator of GetBackers, Psycho Busters is a seven volume manga by Akinari Nao about a group of psychics trying to escape an evil organization bent on ending the world as we know it. While trying to escape, the group is pursued by The Farmers--members of The Greenhouse who capture psychics and perform horrifying experiments on them--and are forced to jump off a cliff (doing so will not kill them because they seem capable of themselves); just as they hit the bottom, the leader, Joi, tells the others to find Kakeru, who is the only one who can help them defeat The Greenhouse once and for all. Meanwhile, Kakeru is left alone for the summer (actually, he was ditched by his mother and sister, who get to go to Hawaii, not that he cares...) when all of a sudden, he finds a beautiful naked girl in his bedroom. Said girl is Ayano, one of the members of the psychic gang trying to escape from The Farmers' clutches. Kakeru soon finds himself joining the group totally unaware of the power he contains deep within him.

The first chapter lampshades several common anime romantic comedy and adventure tropes as Kakeru goes about the house while his family is away.

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