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  • Adored by the Network: Good God.
  • Hey, It's That Voice!: Hoo boy...
    • The sergeant in "Phineas and Ferb Get Busted!" is Clancy Brown, aka Lex Luthor and Mr.Krabs. Clancy also voices a few other characters, such as Santa in the Christmas special and The Regurgitator in "Oh There You Are Perry"
      • In the same episode, Geraldo Rivera voiced an investigative reporter.
    • Riff Raff is the father in the show!
    • Sharp eared fans will recognize Ferb from Doctor Who. He is also the little boy from Love Actually, who has a crush on Vanessa who is voiced by the little girl he fell in love with in that very movie.
    • The early promos for the series jumped on the fact that Ashley Tisdale and Mitchell Musso were providing voices.
      • Particularly amusing when Brenda Song competes with Candace for a job at Mr. Slushy Burger.
        • In in the same episode Brian Stepanek voiced The Slushy Burger Mangaer. Brian Stepanek also played Arwin in the same show.
      • Heck, the fact that Sharpay is best friends with Lady Deathstrike is awesome
    • Ferb's grandfather is voiced by Alex DeLarge and Linderman.
    • Not to mention Jaret Reddick (the lead singer of Bowling for Soup, the band that performed the Phineas and Ferb theme song) as Danny in "Dude, We're Getting the Band Back Together."
      • Speaking of Love Händel, the drummer is Steve Zahn.
      • Jaret also voices himself in a later episode.
    • You may have recognized Linda Flynn's (Mom) voice from her stand-up, as Aunt Hilda and that she hosted The Biggest Loser for quite a few years... if you are of the older audience, of course.
    • How about Rico and Harper as Candace's future kids?
    • Irving is Kenneth the NBC Page.
    • John Dimaggio voices an eccentric circus master in a commercial.
    • Don LaFontaine, announcing the opening of "The Chronicles of Meap"! The episode was one of his last roles in any film or series, and is dedicated to him.

 Don: "In a World!" There, I said it. Happy?

  • Both Marsh and Povenmire wrote for Cat Dog and Rocko's Modern Life. Both shows feature multiple minor characters with the name "Ferb."
  • At least three different cast members from the Rocky Horror Picture Show have starred or guest-starred in the series at least once. Richard O'Brien (Riff Raff) plays the father, Lawrence. Barry Bostwick (Brad Majors ASSHOLE!) plays Phineas's grandfather. And, Tim Curry (Dr. Frank N. Furter) guest-starred as a Mad Scientist in one episode. However, none of the characters nor their voice actors have interacted with each other as of yet.
    • As of "The Last Train to Bustville", Lawrence and Clyde, the grandfather, have had one, very awkward, conversation on camera.
  • Also at least 3 Lexx guest stars: Barry Bostwick (Thodin), Tim Curry (Poet Man), and Malcolm McDowell (Yottskry the Divine Cleric).
  • Ferb's Cousin Eliza fulfills the Grey DeLisle quota for a typical animated show.
  • Phineas and Ferb made a guest appearance in a recent episode of Extreme Makeover: Home Edition in which they build a shrink ray to help Ty Pennington destroy a house. And yes, it is kickass.