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Notable quotes from the One Piece anime and manga series:

Destiny... fate... dreams... These unstoppable ideals are held deep in the heart of man. As long as there are people who seek freedom in this life, these things will not vanish from the earth.
"King of the Pirates" Gold Roger
"When does a man die? Does he die when he's been shot? No. Does he die when he's ravaged with disease? No. Does he die when he's been poisoned? NO! A man dies when, and only when, he is FORGOTTEN! Even when I pass on, my dream will come true! The hearts of the people will be cured...! THIS HAS TRULY BEEN A WONDERFUL LIFE!"
Dr. Hiriluk
They think that.... something so trivial.... can kill me...... I need no assistance....... I..... I am...... I! AM! WHITEBEARD!!!
Whitebeard demonstrating how much of a Made of Iron Determinator Badass Grandpa he is, right before he sweeps aside the marines who had the gall to try and stop him.
If I'm able to meet you again, I'll give you the world's best support as a cook, so that you'll be able to become Pirate King! I'll survive this hell!!!
Sanji makes his pledge to support Luffy while on Kamabakka Island prior to the Time Skip, Chapter 595
I'm sorry...for me to join a team filled with small fries like you will be a waste of my talents!
Nami refusing the offer to leave Luffy's crew for Bellamy's, Chapter 225

Mihawk: Youngster, what is your goal?

Luffy: Pirate King!

Mihawk: (smirks) That is a path of incomparable danger. Even more difficult than to surpass me.

Luffy: I don't care. I will become one anyway!
The two pirates discussing Luffy's dream during the Baratie arc, Chapter 52

Zoro: ...Hey, cook. Give me a hand for 10 seconds.

Sanji: That sounds like the right amount.
The Vitriolic Best Buds about to get serious during the Groggy Ring game, Chapter 311

(Dragon has just helped the Straw Hats escape from Smoker)

Dragon: (laughs) Go! It is your destiny!

Smoker: Why are you helping them, Dragon?

Dragon: What is your reason for stopping them?
Chapter 100

Mihawk: I met some interesting pirates. And that reminds me of that story you told me a long time ago. About one interesting kid from a little village. (holds up Luffy's first bounty poster)

Shanks: .............

(the Red-Hair Pirates light up on recognizing Luffy)

Shanks: (smirks) So you've come, Luffy!
Chapter 96
Zoro: However in exchange! Please take my head instead of his! This I ask of you! It may not be worth as much right now, but this is the head of the man who will be the world's greatest swordsman! Surely thats enough! If you can't even protect your captain, then your ambition is WORTHLESS!! Luffy will be the King of The Pirates!!!
when talking to Kuma on Thriller Bark, begging him to spare Luffy's life
Sanji: I don't intend to run, I don't intend to be killed, I don't intend to forgive you.
to Jabra before using Diablo Jambe for the first time
Luffy: You won't get your way with the seas, or my friends, CAUSE I WON'T LET YOU!!!
to Shiki right before he defeats him

Spandam: What have you done?! Do you really think you can survive with the entire world as your enemy?!?!

Luffy: YOU WANNA BET?!?! Robin, I haven't heard you say it. I want to hear it from your mouth... SAY YOU WANNA LIVE!!

Robin: If I really can say it...if I can have my one selfish wish... I WANNA LIVE! TAKE ME BACK TO SEA TO WITH YOU!!!
Chapter 398

 (Luffy and Zoro have just defeated Helmeppo and Axe-Hand Morgan)

Luffy: Nice, Zoro.

Zoro: It was no trouble, Captain.

Nami: me.
(To Luffy, moments after her Heroic BSOD during the Arlong storyline)
Bellamy: (to Luffy) Can you fight? Can you even throw a punch?
(cue One Hit KO moments later)

 Donquixote Doflamingo: Pirates are evil? The Marines are righteous? These terms have always changed throughout the course of history! Kids who have never seen peace and kids who have never seen war have different values! Those who stand at the top determine what's wrong and what's right! This very place is neutral ground! Justice will prevail, you say? But of course it will! Whoever wins this war...becomes justice!

Zoro: Whatever the thoughts were in Luffy and Usopp's argument, and no matter who was correct, as long as the two decided to fight, the outcome was entrusted to the match. In the end, (Usopp) lost...and left us. (taps Luffy on the head) Listen, guys. Even though (Luffy)'s such an idiot, he is our captain. It's better not to have someone who cannot pay due respect to him when there's something in our crew...! A crew whose captain has lost his dignity will surely collapse!!! (to Luffy) It's none of my business that you usually joke around, but if you humiliate yourself yet still want to claim any pretense of being my leader, THEN I WILL BE THE ONE TO LEAVE THE CREW THIS TIME!!!
part of his What the Hell, Hero? speech on Usopp's rejoining, Chapter 438

 (Luffy has just fought Usopp over the Going Merry's fate)

Luffy: (on the verge of crying) It's heavy...

Zoro: That is a captain's burden. Don't hesitate. Who are we going to rely on if you falter?

Weaklings don't get to choose how they die.

 (Skypiea arc, chapter 280, during the fight with Eneru on board the Maxim)

Nami: (to herself, in a panic) This is bad! I can't escape like this! Luffy, hurry up and take down Eneru! Wait...what if the ship falls from the sky when Eneru gets defeated? No, if we don't stop Eneru, the Sky Island will be gone for good! What should I do?! (aloud, to Luffy) What should we do, Luffy? We...

Luffy: (tosses Nami his hat) Quit yapping!

Nami: But...

Luffy: You are the future Pirate King's friend, so stop being such a worrier!

Eneru: Pirate King? What country does he rule?

Luffy: He is the king of the sea!

Eneru: That doesn't sound half bad...Let's finish this in the sky.

Don't start a fight you can't finish.
Sanji's Pre-Ass-Kicking One-Liner to the Franky Family
It's not some kind of special power, but he (Luffy) has the ability to make allies of everyone he meets. And that is the most fearsome power on these high seas!
Mihawk, on seeing Luffy's fighting force of friends and past foes at Marineford

Sanji: Oi, what happened here?!

Zoro: Nothing...nothing at all.
during Thriller Bark, moments after Zoro has absorbed all of Luffy's pain and fatigue

 (a little girl has just bumped into Smoker and spilled her ice cream on his pants)

Smoker: seems my pants ate your ice cream. (gives her money) Buy yourself five scoops this time.

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