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Best known for her work on The Simpsons, Nancy Cartwright has been doing cartoon voices since Hanna-Barbera's version of Richie Rich in the early 1980s. She is also an animation producer, responsible for's Web Animation series The Kellys. She has adapted her book, My Life as a 10-Year-Old Boy, into an audiobook and a one-woman stage show.

Cartwright has also appeared in live action, including Joe Dante's segment of Twilight Zone the Movie and the Made for TV Movie Marian Rose White, and the American Godzilla movie (which also had Hank Azaria and Harry Shearer of The Simpsons). She even was a celebrity guest on Tom Bergeron's Hollywood Squares and Donny Osmond's Pyramid. Outside show business, Cartwright is a prominent member of the Church of Scientology.

Cartwright has done character voices for the following animated series:

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