Mostly Harmless could refer to...
- The Hitchhiker's Guide to the Galaxy/Mostly Harmless, a sequel book and Catch Phrase in The Hitchhikers Guide to The Galaxy
- Mostly Harmless (TV series), a public-access sketch comedy show from Connecticut, U.S.A.
- Mostly Harmless (roleplay), a Live Journal roleplay set in the H2G2 universe
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