Five-Man Band/Video Games T-Z

Tales of Destiny

The Hero	Stahn
The Lancer	Leon, Rutee ( After Leon dies)
The Big Guy	Woodrow/Garr
The Smart Guy and The Chick	Philia

Tales of Eternia

The Hero	Farah
The Lancer	Reid
The Big Guy	Max
The Smart Guy(s)	Keele and Chat
The Chick	Meredy
Sixth Ranger Traitor	Ras
The Mentor	Galenos
Team Pet	Quickie

Tales of Graces

The Hero	Asbel
The Lancer	Malik
The Big Guy	Sophie
The Smart Guy	Pascal
The Chick	Cheria
The Sixth Ranger	Hubert

Tales of Hearts

The Hero	Shing
The Lancer	Hisui
The Big Guy(s)	Innes, Kunzite
The Smart Guy(s)	Kunzite, Innes
The Chick(s)	Kohak, Beryl
Mysterious Waif	Richea
Sixth Ranger	Chalcedny Squad

Tales of Innocence

The Hero	Ruca
The Lancer	Spada
The Big Guy	Hermana
The Smart Guy	Ricardo
The Chick(s)	Iria, Ange
Team Pet	Kouda

Tales of Phantasia

The Hero	Cless
The Lancer	Chester
The Smart Guy	Klarth
The Big Guy	Arche (magic type)
The Chick	Mint
Sixth Ranger	Suzu (only available in re-releases of the game)

Tales of Symphonia - Initial Guard

The Hero	Lloyd
The Lancer	Genis
The Smart Guy	Raine
The Big Guy	Kratos
The Chick	Colette
Sixth Ranger(s)	Sheena, Zelos, Presea and Regal

Tales of Vesperia

The Hero	Yuri
The Lancer	Judith
The Big Guy	Karol (who incidentally happens to be a 12-year-old kid.)
The Smart Guy	Rita
The Chick	Estelle
Sixth Ranger	Raven
Team Pet	Repede

Throne of Darkness has seven men, of whom the player can control 4 at a time, while the others are resting. The ideal combination looks something like this:

The Hero	The Leader
The Lancer	The Swordsman or The Archer
The Big Guy(s)	The Brick and The Berserker
The Smart Guy	The Vizard or The Ninja

Tomb Raider: Legend

The Hero	Lara
The Lancer	Winston
The Big Guy	Zip
The Smart Guy	Alister
The Chick	Anaya

Touch Detective

The Hero	Mackenzie
The Lancer	Chloe
The Smart Guy	Cromwell
The Chick	Penelope
Team Pet	Fungi

Touhou (as of Subterranean Animism)

The Hero	Reimu
The Lancer	Marisa
The Smart Guy	Nitori and Patchouli
The Big Guy	Suika
The Chick	Alice
Sixth Ranger	Aya and Sanae
The Mentor	Yukari
Team Pet	Rinnosuke

The semi-canonical TouhouTeam 9 is as follows:

The Hero	Cirno (Idiot Hero)
The Lancer	Wriggle
The Smart Guy	Mystia
The Big Guy	Daiyousei
The Chick and Token Evil Teammate	Rumia

• Note: See also Five-Bad Band for some of the boss teams in Touhou Project, who can technically fit here due to the games' White and Grey Morality.

Trauma Team

The Hero	CR-S01
The Lancer	Maria Torres
The Big Guy	Hank Freebird (literally - his intro mission is called "The Big Guy")
The Smart Guy	Gabriel Cunningham
The Chick	Tomoe Tachibana
Sixth Ranger	Naomi Kimishima

Valkyria Chronicles

The Hero	Welkin
The Lancer	Alicia
The Big Guy	Largo
The Smart Guy	Isara
The Chick	Rosie

Valkyrie Profile 2 (at first)

The Hero	Silmeria
The Lancer	Rufus
The Big Guy	Dylan
The Smart Guy	Lezard
The Chick	Alicia
Sixth Ranger	Leone (real identity Hrist) and Arngrim

Watch Dogs 2

The Hero	Marcus Holloway
The Lancer	Josh Sauchak
The Smart Guy	Wrench
The Big Guy	Horatio Carlin
The Chick	Sitara Dhawan

Wild ARMs

The Hero	Rudy (also the closest the group has to The Big Guy)
The Lancer	Jack
The Chick	Cecilia
The Smart Guy	Hanpan

The remake expands upon this to make it a full on 6 man team....er...5 with pet:

Wild ARMS Alter Code F

The Hero	Rudy
The Lancer	Jack
The Smart Guy	Emma
Action Girl	Jane
The Chick	Cecilia
The Sixth Ranger	Zed
Team Pet	Hanpan

Wild Arms 2

The Hero	Ashley Winchest
The Big Guy	Brad Evans
The Lancer	Kanon
The Chick	Lilka Eleniak
Kid Appeal Character	Tim Rhymeless
The Sixth Ranger	Marivel Armitage

Wild Arms 3

The Hero / The Chick	Virginia
The Lancer	Jet
The Big Guy	Gallows
The Smart Guy	Clive

Wild Arms 4

The Hero	Jude Maverick
The Lancer and The Smart Guy	Arnaud G. Vasquez
The Big Guy	Raquel Applegate
The Chick	Yulie Ahtreide
Sixth Ranger	Kresnik Ahtreide

Wild Arms 5

The Hero	Dean
The Lancer	Rebecca
The Big Guy	Greg
The Smart Guy	Avril
The Chick	by virtue of process of elimination... Chuck
Tagalong Kid	Carol

• In this case, I'm fully aware that the choices for The Smart Guy and The Chick are in YMMV territory, please feel free to suggest changes.

The Witcher 2: Assassins of Kings

The Hero	Geralt of Rivia
The Lancer	Vernon Roche or Iorveth
The Big Guy	Zoltan Chivay
The Smart Guy	Dandelion
The Chick	Triss Merigold

The World Ends With You

The Hero	Neku
The Lancer	Shiki
The Smart Guy	Joshua
The Big Guy	Beat
The Chick	Rhyme

And, in the Alternate Universe bonus chapter:

The Hero	Shooter
The Lancer	Neku
The Smart Guy	Joshua
The Big Guy	Beat
The Chick	Shiki
Sixth Ranger Traitor	Rhyme

World of Warcraft

Character Classes

The Hero	The Tank, leader and protector of the group.
The Lancer	The Rogue, cat Druid and Hunter. Their methods are basically the opposite of the tank's, yet they're on the same side.
The Big Guy	The Warrior, Paladin, balance Druid and Shaman. Whether it's because of heavy weapons and armor or hard hitting primal magic, these guys are anything but subtle.
The Smart Guy	The Mage, Warlock, and Priest. They're Squishy Wizards with unique and varied magic.
The Chick	The Healer, who deals little to no damage but instead keeps the group in a fit state to continue.
The Sixth Ranger	The Death Knight, who joins the fight later in the timeline than the others. The Monk as of Mists of Pandaria.

Alliance

The Hero	Varian Wrynn
The Lancer	Magni Bronzebeard Muradin Bronzebeard in Cataclysm
The Smart Guy	Gelbin Mekkatorque
The Big Guy	Tyrande Whisperwind
The Chick	Velen or Jaina Proudmoore
Sixth Ranger	Genn Greymane
Tagalong Kid	Anduin Wrynn

Alliance Expedition

The Hero	Turalyon
The Lancer	Danath Trollbane
The Smart Guy	Khadgar
The Big Guy	Kurdran Wildhammer
The Chick	Alleria Windrunner Horde
The Hero	Thrall
The Lancer	Vol'jin
The Smart Guy	Lor'themar Theron
The Big Guy	Cairne Bloodhoof ( later replaced by Baine after Cairne dies)
The Dark Chick	Sylvanas Windrunner
Sixth Ranger	Trade Prince Gallywix (temporarily appointed by Thrall)

The Artists Formerly Known as Level 80 Elite Tauren Chieftain

The Hero	Samuro
The Lancer	Bergrisst
The Big Guy	Chief Thunder-Skins
The Smart Guy	Mai'Kyl
The Chick	Sig Nicious

Syphon Filter: The Omega Strain

The Hero	Cobra
The Lancer	Gabe Logan
The Big Guy	Gary Stoneman
The Smart Guy	Teresa Lipan
The Chick	Lian Xing
The Mentor	Imani Gray
The Sixth Ranger	Lawrence Mujari

Winback

The Hero	Jean-Luc Cougar
The Lancer	Jake Hudson
The Smart Guy	Tom Smith
The Big Guy	Law Bruford
The Chick	Lisa Roberts
The Sixth Ranger	Mike Hawkins
Tagalong Kid	Keith Birdy
The Mentor	Steven Legal

Xenosaga - Main party

The Hero	Shion Uzuki
The Lancer	Jr.
The Big Guy	Ziggy and KOS-MOS
The Smart Guy	Chaos
The Chick	MOMO
The Sixth Ranger	Jin Uzuki

Ys Book I and II: Ancient Ys Vanished

The Hero	Adol
The Lancer	Goban
The Big Guy	Dogi
The Smart Guy	Luta
The Chick	Lilia
The Mysterious Waif(s)	Feena and Lair
The Sixth Ranger Traitor	Keith

Ys: The Ark of Napishtim

The Hero	Adol
The Lancer	Dogi
The Big Guy	Chief Ord
The Smart Guy	Ur
The Chick	Olha
The Cute Bruiser	Terra
The Tagalong Kid	Isha
The Rival	Geis
The Obi-Wan	Raba

zOMG! features a number of ring classes that may fit the trope.

The Hero	Melee - Single Target
The Lancer	Buffs
The Big Guy	Melee - Area of Effect
The Smart Guy(s)	Crowd Control, Healing (sometimes The Chick)
The Chick	Ranged

Zork: Grand Inquisitor

The Hero	AFGNCAAP
The Lancer	Dalboz of Gurth
The Big Guy	Brog
The Smart Guy	Griff
The Chick	Lucy Flathead
The Sixth Ranger	Antharia Jack