Snake: Colonel, I need you to describe seiyuu here for me.
Colonel: You want to know about David Hayter, huh, Snake?
Snake: Huh? No, not my English voice actor, Colonel, but my 'seiyuu', the Japanese equivalent of a voice actor.
Colonel: Oh, right. My mistake. Akio Ohtsuka is one of the most respected seiyuu veterans in the business. He's the son of another veteran seiyuu, Chikao Ohtsuka (who's still active), making him an old son. Until a few years ago, he was also married to another seiyuu, Yoko Soumi, known for her Vamp, serious lady or Femme Fatale roles (like Karen Kasumi from X 1999 the TV series, Atsuko from Yu Yu Hakusho).
Snake: So he's part of seiyuu royalty, eh? I wouldn't be surprised if his kids became seiyuus as well.
Colonel: Known for a deep, gruff voice that fits him into veteran-like roles, Akio often lands characters who are widely considered Badass, making him quite a fan favorite amongst older seiyuus. He'll gladly do humor roles, as well.
Snake: Going from serious to humorous, eh? Wouldn't it be best to stick to one role?
Notable roles by Akio Ohtsuka:
- Solid Snake and Naked Snake aka the young Big Boss in Metal Gear Solid.
- Also the voice of Solidus Snake in Metal Gear Solid 2 Sons of Liberty.
- Dr. Black Jack in Black Jack
- Anavel Gato in Mobile Suit Gundam 0083 Stardust Memory, Super Robot Wars F, Super Robot Wars Alpha 1 and 2, Super Robot Wars Impact and Super Robot Wars Advance Portable
- Elmer Snell in Mobile Suit Gundam MSIGLOO 2: The Gravity Front
- Vice-Foreign Minister Darlian and the Narrator in Mobile Suit Gundam Wing
- Kyoraku Shunsui in the Bleach franchise
- Windam in Magic Knight Rayearth
- Souther/Thouzer in Fist of the North Star (Movie version; succeeds Banjo Ginga, who is ironically Liquid Snake)
- Judge Gabranth in Final Fantasy XII and Dissidia Final Fantasy
- Amano Hyo in Last Blade
- Honda Tadakatsu in the Samurai Warriors franchise
- Regal Bryant in Tales of Symphonia
- Radi Yaeger in Valkyria Chronicles
- Rider (Alexander the Great) in Fate/Zero
- Seth in Street Fighter IV
- Batou in the Ghost in the Shell franchise
- Mihai in the DOGS Bullets and Carnage OVA
- Gio in Atelier Rorona and Meruru
- Siam in Canaan
- Blackbeard in One Piece
- Han Solo (Harrison Ford) in the Japanese dub of Star Wars
- Jules Winfield (Samuel L. Jackson) in the Japanese dub of Pulp Fiction
- "Ansem"/Xehanort in Kingdom Hearts
- Gwendal von Voltaire in Kyo Kara Maoh
- Souichi "Ironman" Nishimura in Baka to Test to Shoukanjuu
- Kishitani Shingen in Durarara
- Daigo Kazama in Project Justice, replacing Koichi Yamadera
- Laike in Lunar: Silver Star Story
- Bobby in the Japanese dub of Animaniacs
- Leo Johnson (Eric DaRe) in the Japanese dub of Twin Peaks
- Boss in Twelve Riven
- Mario Auditore in Assassin's Creed II
- Morrison in Devil May Cry the Animated Series
- The eponymous vampire hunter Blade
- Boy in Yarudora series vol.3: Sampaguita
- Mel Gibson
His English counterpart is Crispin Freeman.